Endothéline-1, angiotensine II et cancer

Et tu bipolar II?

There is currently lively debate as regards the diagnosis of bipolar disorder. Generally, there is consensus that bipolar I disorder, characterised by mania, is distinct as compared to unipolar major depression. This is demonstrated to some extent across the phenomenology, population characteristics, genetics and neurobiology of the two phenotypes. However, the diagnosis of bipolar II disorder ...

سطح اندوتلین-1 (ET-1) در بیماران مبتلا به اسکلرودرمی با و بدون زخم نوک انگشتان

مقدمه: اسکلرودرمی یک اختلال سیستمیک با علل ناشناخته می باشد که با ضخیم شدن پوست و درگیری ارگان های داخلی مشخص می شود. اندوتلین-1 (ET-1) در فیبروزی شدن پوست بیماران مبتلا موثر می باشد. این مطالعه با هدف بررسی سطح اندوتلین-1 در بیماران مبتلا به اسکلرودرمی با زخم نوک انگشتان و مقایسه آن با بیماران مبتلا به اسکلرودرمی بدون زخم نوک انگشتان انجام شده است. روش کار: مطالعه حاضر از نوع توصیفی- تحلیلی اس...

Purification et concentrations des plasmas antitoxiques. 1 - Historique, techniques industrielles et choix de la méthode adoptee en Iran

1. HA NGGADA et al

10 cases . The histopathology laboratory of the UMTH provides referral services for all the hospitals and private clinics in Borno State as well as other neighbouring States in the northeastern part of Nigeria. Therefore, the aim of this study was to provide baseline data on the frequency of occurrence, age and parity of patients, clinical presentation, degenerative changes, diseases associated...

Stimulation of colorectal cancer cell line growth by ET-1 and its inhibition by ET(A) antagonists.

BACKGROUND The vasoactive peptide endothelin 1 (ET-1) acts via two receptors, endothelin receptors A (ET(A)) and B (ET(B)). ET-1 is overexpressed by human cancers in vivo and in vitro and may be mitogenic for cancer cells. METHOD To elucidate if ET-1 is a growth regulator the following were investigated in human colorectal cancer cell lines (LIM1215 and HT29): ET-1 production by ELISA; ET rec...